Peripheral Neuropathy
March 2021 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Trends in Pain Medication Initiation Among Patients With Newly Diagnosed Diabetic Peripheral Neuropathy, 2014-2018.
Authors:Fan J, Jeffery MM, Hooten WM, Shah ND, McCoy RG
Institution:Division of Digital Health Sciences, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota. Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota.
Journal:JAMA Netw Open. 2021 Jan 4;4(1):e2035632. doi: 10.1001/jamanetworkopen.2020.35632.

2:Quality of life in chronic inflammatory demyelinating polyneuropathy patients treated with subcutaneous immunoglobulin.
Authors:Ryltoft AK, Al-Zuhairy A, Sindrup SH, Andersen H, Markvardsen LK
Institution:Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.
Journal:Acta Neurol Scand. 2020 Dec;142(6):637-640. doi: 10.1111/ane.13322. Epub 2020 Aug 5.

3:Peripheral Neuropathy: Evaluation and Differential Diagnosis.
Authors:Castelli G, Desai KM, Cantone RE
Institution:University of Pittsburgh Medical Center St. Margaret, Pittsburgh, PA, USA. Oregon Health and Science University, Portland, OR, USA.
Journal:Am Fam Physician. 2020 Dec 15;102(12):732-739.

4:Peripheral Neuropathy and All-Cause and Cardiovascular Mortality in U.S. Adults : A Prospective Cohort Study.
Authors:Hicks CW, Wang D, Matsushita K, Windham BG, Selvin E
Institution:Johns Hopkins University School of Medicine, Baltimore, Maryland (C.W.H.). Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (D.W., K.M., E.S.).
Journal:Ann Intern Med. 2021 Feb;174(2):167-174. doi: 10.7326/M20-1340. Epub 2020 Dec 8.

5:Effect of resistance exercise on peripheral neuropathy in Type 2 diabetes mellitus.
Authors:Yang X, Liu L, Yang L, Li W, Zhang J
Institution:Department of Endocrinology, Punan Hospital, Pudong New Area, Shanghai 200125, China. Department of Endocrinology, Punan Hospital, Pudong New Area, Shanghai 200125, China.
Journal:Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Oct 28;45(10):1185-1192. doi: 10.11817/j.issn.1672-7347.2020.190505.

6:Home-based subcutaneous immunoglobulin for chronic inflammatory demyelinating polyneuropathy patients: A Swiss cost-minimization analysis.
Authors:Perraudin C, Bourdin A, Vicino A, Kuntzer T, Bugnon O, Berger J
Institution:Community Pharmacy, Center for Primary Care and Public Health (Unisante), University of Lausanne, Lausanne, Switzerland.
Journal:PLoS One. 2020 Nov 25;15(11):e0242630. doi: 10.1371/journal.pone.0242630. eCollection 2020.

7:Non-invasive neuromodulation effects on painful diabetic peripheral neuropathy: a systematic review and meta-analysis.
Authors:Zeng H, Pacheco-Barrios K, Cao Y, Li Y, Zhang J, Yang C, Fregni F
Institution:Department of Endocrinology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, 261 Datong Road, Er Sha Island, Guangzhou, 510105, China. Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, 96 13th Street, Charlestown, Boston, MA, USA.
Journal:Sci Rep. 2020 Nov 5;10(1):19184. doi: 10.1038/s41598-020-75922-9.

8:Moxibustion for the treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis following PRISMA guidelines.
Authors:Tan Y, Hu J, Pang B, Du L, Yang Y, Pang Q, Zhang M, Wu Q, Zhang Y, Ni Q
Institution:Department of Endocrinology.
Journal:Medicine (Baltimore). 2020 Sep 25;99(39):e22286. doi: 10.1097/MD.0000000000022286.

9:8% Capsaicin Patch in Treatment of Peripheral Neuropathic Pain.
Authors:Goncalves D, Rebelo V, Barbosa P, Gomes A
Institution:Department of Anesthesiology., Centro Hospitalar de Leiria, EPE, Leiria, Portugal.
Journal:Pain Physician. 2020 Sep;23(5):E541-E548.

10:Chronic inflammatory axonal polyneuropathy.
Authors:Oh SJ, Lu L, Alsharabati M, Morgan MB, King P
Institution:Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Journal:J Neurol Neurosurg Psychiatry. 2020 Nov;91(11):1175-1180. doi: 10.1136/jnnp-2020-323787. Epub 2020 Sep 11.

11:Pulse oral corticosteroids in pediatric chronic inflammatory demyelinating polyneuropathy.
Authors:Rogers AB, Zaidman CM, Connolly AM
Institution:Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA. Department of Pediatrics, Neurology Division, Nationwide Children's Hospital, Ohio State University, Columbus, Ohio, USA.
Journal:Muscle Nerve. 2020 Dec;62(6):705-709. doi: 10.1002/mus.27058. Epub 2020 Oct 2.

12:Association of Peripheral Neuropathy with Erectile Dysfunction in US Men.
Authors:Hicks CW, Wang D, Windham BG, Selvin E
Institution:Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins University School of Medicine, Baltimore, Md. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore Md.
Journal:Am J Med. 2021 Feb;134(2):282-284. doi: 10.1016/j.amjmed.2020.07.015. Epub 2020 Aug 14.

13:Prevalence and Predictors of Distal Symmetric Polyneuropathy in Patients with HIV/AIDS not on Highly Active Anti Retroviral Therapy (HAART).
Authors:Gupta PK, Varun V, Mahto SK, Hansraj, Anand KS, Taneja RS, Shrama N, Vishal A
Institution:Professor, Dept. of Neurology, PGIMER, ABVIMS, and Dr. RML Hospital, New Delhi.
Journal:J Assoc Physicians India. 2020 Sep;68(9):23-26.

14:Oral pharmacotherapeutics for the management of peripheral neuropathic pain conditions - a review of clinical trials.
Authors:Knezevic NN, Jovanovic F, Candido KD, Knezevic I
Institution:Department of Anesthesiology, Advocate Illinois Masonic Medical Center , Chicago, IL, US.
Journal:Expert Opin Pharmacother. 2020 Dec;21(18):2231-2248. doi: 10.1080/14656566.2020.1801635. Epub 2020 Aug 9.

15:Fatigue in chronic inflammatory demyelinating polyneuropathy.
Authors:Gable KL, Attarian H, Allen JA
Institution:Department of Neurology, Duke University Medical Center, Durham, North Carolina, USA. Department of Neurology, Northwestern University, Chicago, Illinois, USA.
Journal:Muscle Nerve. 2020 Dec;62(6):673-680. doi: 10.1002/mus.27038. Epub 2020 Aug 10.

16:Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update.
Authors:Loprinzi CL, Lacchetti C, Bleeker J, Cavaletti G, Chauhan C, Hertz DL, Kelley MR, Lavino A, Lustberg MB, Paice JA, Schneider BP, Lavoie Smith EM, Smith ML, Smith TJ, Wagner-Johnston N, Hershman DL
Institution:Mayo Clinic, Rochester, MN. Columbia University Medical Center, New York, NY.
Journal:J Clin Oncol. 2020 Oct 1;38(28):3325-3348. doi: 10.1200/JCO.20.01399. Epub 2020 Jul 14.

17:Peripheral neuropathy and depressive symptoms: examining the association in a primary health care setting among persons with and without diabetes mellitus.
Authors:Benavidez GA, Ylitalo KR, Lanning B, Asare M, Meyer A, Griggs JO
Institution:Department of Public Health, Baylor University, One Bear Place #97343, Waco, TX, 76798, USA. Waco Family Health Center, 1600 Providence Dr, Waco, TX, 76707, USA.
Journal:Qual Life Res. 2020 Dec;29(12):3297-3304. doi: 10.1007/s11136-020-02579-2. Epub 2020 Jul 10.

18:Peripheral Neuropathy in the Lower Limbs of Individuals With Spinal Cord Injury or Disease: A Retrospective Study.
Authors:Liang J, Furlan JC
Institution:From the Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Toronto, Toronto, Ontario, Canada (JL, JCF); and KITE - Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada (JCF).
Journal:Am J Phys Med Rehabil. 2021 Jan 1;100(1):57-64. doi: 10.1097/PHM.0000000000001518.

19:Pain in Patients With Type 2 Diabetes-Related Polyneuropathy Is Associated With Vascular Events and Mortality.
Authors:Lapin BR, Pantalone KM, Milinovich A, Morrison S, Schuster A, Boulos F, Johnson K, Thakore NJ
Institution:Center for Outcomes Research and Evaluation, Neurological Institute, Cleveland Clinic, Cleveland, Ohio. Department of Neurology/Neuromuscular Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio.
Journal:J Clin Endocrinol Metab. 2020 Sep 1;105(9):dgaa394. doi: 10.1210/clinem/dgaa394.

20:Peripheral neuropathy in mixed cryoglobulinaemia: clinical assessment and therapeutic approach.
Authors:Scarpato S, Galassi G, Monti G, Mazzaro C, Mascia MT, Scaini P, Filippini D, Pietrogrande M, Galli M
Institution:Rheumatology Unit, Lupus Clinic M. Scarlato Hospital, Scafati, Italy. Clinica delle Malattie Infettive, L. Sacco Department of Biomedical and Clinical Sciences, University of Milan, Italy.
Journal:Clin Exp Rheumatol. 2020 Nov-Dec;38(6):1231-1237. Epub 2020 Jun 23.

21:Painful and non-painful chemotherapy-induced peripheral neuropathy and quality of life in colorectal cancer survivors: results from the population-based PROFILES registry.
Authors:Bonhof CS, Trompetter HR, Vreugdenhil G, van de Poll-Franse LV, Mols F
Institution:CoRPS - Center of Research on Psychology in Somatic Disorders, Department of Medical and Clinical Psychology, Tilburg University, PO Box 90153, 5000, LE, Tilburg, the Netherlands.
Journal:Support Care Cancer. 2020 Dec;28(12):5933-5941. doi: 10.1007/s00520-020-05438-5. Epub 2020 Apr 12.

22:Taxane-induced peripheral neuropathy: differences in patient report and objective assessment.
Authors:Timmins HC, Li T, Kiernan MC, Baron-Hay S, Marx G, Boyle F, Goldstein D, Park SB
Institution:Brain and Mind Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, 2050, Australia.
Journal:Support Care Cancer. 2020 Sep;28(9):4459-4466. doi: 10.1007/s00520-020-05299-y. Epub 2020 Jan 11.

23:Adaptation of perturbation to postural control in individuals with diabetic peripheral neuropathy.
Authors:Kim BBJ, Kim S
Institution:Department of Engineering, East Carolina University, USA.
Journal:Int J Occup Saf Ergon. 2020 Sep;26(3):589-594. doi: 10.1080/10803548.2018.1494771. Epub 2018 Aug 7.

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What Our Customers Are Saying...

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