Peripheral Neuropathy
September 2018 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Fasudil combined with methylcobalamin or lipoic acid can improve the nerve conduction velocity in patients with diabetic peripheral neuropathy: A meta-analysis.
Authors:Jiang DQ, Xu LC, Jiang LL, Li MX, Wang Y
Institution:College of Biology and Pharmacy, Yulin Normal University. Yulin. University, Hangzhou. Guangzhou, China.
Journal:Medicine (Baltimore). 2018 Jul;97(27):e11390. doi: 10.1097/MD.0000000000011390.

2:ACUDIN - ACUpuncture and laser acupuncture for treatment of DIabetic peripheral Neuropathy: a randomized, placebo-controlled, partially double-blinded trial.
Authors:Meyer-Hamme G, Friedemann T, Greten HJ, Plaetke R, Gerloff C, Schroeder S
Institution:HanseMerkur Center for Traditional Chinese Medicine at the University Medical Center Hamburg-Eppendorf, Martinistrasse 52, House O55, 20246, Hamburg, Germany. Center Hamburg-Eppendorf, Martinistrasse 52, House O55, 20246, Hamburg, Germany. Germany. University of Porto, Rua de Jorge Viterbo Ferreira n. 228, 4050, -313, Porto, Portugal. Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany. Martinistrasse 52, 20246, Hamburg, Germany.
Journal:BMC Neurol. 2018 Apr 13;18(1):40. doi: 10.1186/s12883-018-1037-0.

3:Association between diabetic peripheral neuropathy and heart rate variability in subjects with type 2 diabetes.
Authors:Islam SKMA, Kim D, Lee YS, Moon SS
Institution:Department of Internal Medicine, Dongguk University College of Medicine, Gyeongju, South Korea. Korea. Gyeongju, South Korea. Gyeongju, South Korea. Electronic address: drmoonss@hanmail.net.
Journal:Diabetes Res Clin Pract. 2018 Jun;140:18-26. doi: 10.1016/j.diabres.2018.03.034. Epub 2018 Mar 26.

4:Two-Point Discrimination Predicts Pain Relief after Lower Limb Nerve Decompression for Painful Diabetic Peripheral Neuropathy.
Authors:Wang Q, Guo ZL, Yu YB, Yang WQ, Zhang L
Institution:Beijing and Qingdao, People's Republic of China From Peking University China-Japan Friendship School of Clinical Medicine; the Department of Neurosurgery, China-Japan Friendship Hospital; and the Department of Rehabilitation, the Affiliated Hospital of Qingdao University.
Journal:Plast Reconstr Surg. 2018 Mar;141(3):397e-403e. doi: 10.1097/PRS.0000000000004171.

5:A novel curcumin derivative for the treatment of diabetic neuropathy.
Authors:Daugherty DJ, Marquez A, Calcutt NA, Schubert D
Institution:The Salk Institute for Biological Studies, La Jolla, CA, USA. Electronic address: Schubert@salk.edu.
Journal:Neuropharmacology. 2018 Feb;129:26-35. doi: 10.1016/j.neuropharm.2017.11.007. Epub 2017 Nov 6.

6:Severity of Neuropathy Is Associated With Long-term Spinal Cord Stimulation Outcome in Painful Diabetic Peripheral Neuropathy: Five-Year Follow-up of a Prospective Two-Center Clinical Trial.
Authors:van Beek M, Geurts JW, Slangen R, Schaper NC, Faber CG, Joosten EA, Dirksen CD, van Dongen RT, van Kuijk SMJ, van Kleef M
Institution:Department of Anesthesiology and Pain Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands m.vanbeek@maastrichtuniversity.nl maarten.van.kleef@mumc.nl.; Department of Anesthesiology and Pain Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.; Department of Anesthesiology, Rijnstate Hospital, Arnhem, the Netherlands.; Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.; Department of Neurology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Journal:Diabetes Care. 2018 Jan;41(1):32-38. doi: 10.2337/dc17-0983. Epub 2017 Nov 6.

7:Diabetic polyneuropathy, deep white matter lesions, and carotid atherosclerosis: is there any association?
Authors:Ferik S, Guven H, Ates MP, Conkbayir I, Comoglu S, Guven B
Institution:Diskapi Yildirim Beyazit Training and Research Hospital, Department of Neurology, University of Health Sciences, Cigdem mah. 1550/1 cad. 23/1 Cankaya, 06530, Ankara, Turkey.
Journal:Neurol Sci. 2018 Jan;39(1):103-110. doi: 10.1007/s10072-017-3160-x. Epub 2017 Oct 23.

8:The efficacy of removable devices to offload and heal neuropathic plantar forefoot ulcers in people with diabetes: a single-blinded multicentre randomised controlled trial.
Authors:Bus SA, van Netten JJ, Kottink AI, Manning EA, Spraul M, Woittiez AJ, van Baal JG
Institution:Department of Surgery, Ziekenhuisgroep Twente, Almelo and Hengelo, the Netherlands. Amsterdam, Amsterdam Movement Sciences, Amsterdam, the Netherlands. Netherlands. Netherlands. Netherlands. Netherlands. Netherlands.
Journal:Int Wound J. 2018 Feb;15(1):65-74. doi: 10.1111/iwj.12835. Epub 2017 Oct 23.

9:Efficacy and safety of pregabalin for painful diabetic peripheral neuropathy in a population of Chinese patients: A randomized placebo-controlled trial.
Authors:Mu Y, Liu X, Li Q, Chen K, Liu Y, Lv X, Xu X, Fan D, Shang N, Yang R, Pauer L, Pan C
Institution:Department of Endocrinology, Chinese PLA General Hospital, Beijing, China. University, Harbin, China. Beijing, China. Chongqing, China. China. Region, Beijing, China. Nanjing, China. Pfizer, Beijing, China. Connecticut, USA.
Journal:J Diabetes. 2018 Mar;10(3):256-265. doi: 10.1111/1753-0407.12585. Epub 2017 Nov 1.

10:Effects of acetyl-L-carnitine in diabetic neuropathy and other geriatric disorders.
Authors:Sergi G, Pizzato S, Piovesan F, Trevisan C, Veronese N, Manzato E
Institution:Department of Medicine - DIMED, University of Padova, Padova, Italy. simonapizzato@yahoo.it.
Journal:Aging Clin Exp Res. 2018 Feb;30(2):133-138. doi: 10.1007/s40520-017-0770-3. Epub 2017 May 22.

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