Peripheral Neuropathy
July 2019 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Peripheral Neuropathy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Peripheral Neuropathy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Peripheral Neuropathy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Peripheral Neuropathy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Work ability and productivity in patients with diabetic foot.
Authors:Cabeceira HDS, Souza DMST, Juliano Y, Veiga DF
Institution:Mestrado Profissional em Ciencias Aplicadas a Saude, Universidade do Vale do Sapucai (UNIVAS), Pouso Alegre, MG, BR. Universidade do Vale do Sapucai (UNIVAS), Pouso Alegre, MG, BR. Alegre, MG, BR. Saude, Universidade do Vale do Sapucai (UNIVAS), Pouso Alegre, MG, BR.
Journal:Clinics (Sao Paulo). 2019 Mar 25;74:e421. doi: 10.6061/clinics/2019/e421.

2:How We Treat Autoimmune Small Fiber Polyneuropathy with Immunoglobulin Therapy.
Authors:Schofield JR, Chemali KR
Institution:Center for Multisystem Disease, Denver, Colorado, USA, Colorado, USA,
Journal:Eur Neurol. 2018;80(5-6):304-310. doi: 10.1159/000498858. Epub 2019 Mar 19.

3:The diabetic foot: Pathophysiology, evaluation, and treatment.
Authors:Bandyk DF
Institution:Division of Vascular and Endovascular Surgery, University of California-San Diego, 9434 Medical Center Drive, Mail Code 7403, La Jolla, CA 92037. Electronic address:
Journal:Semin Vasc Surg. 2018 Jun - Dec;31(2-4):43-48. doi: 10.1053/j.semvascsurg.2019.02.001. Epub 2019 Feb 6.

4:Review on Wearables to Monitor Foot Temperature in Diabetic Patients.
Authors:Martin-Vaquero J, Hernandez Encinas A, Queiruga-Dios A, Jose Bullon J, Martinez-Nova A, Torreblanca Gonzalez J, Bullon-Carbajo C
Institution:Department of Applied Mathematics, University of Salamanca, E37008 Salamanca, Spain. Spain. Spain. Salamanca, Spain.
Journal:Sensors (Basel). 2019 Feb 14;19(4). pii: s19040776. doi: 10.3390/s19040776.

5:Neurologic Conditions: Common Peripheral Neuropathies.
Authors:McKinley JE, Perkins A
Institution:Crestwood Medical Center, 1 Hospital Drive Southwest, Huntsville, AL 35801. 1601 Center Street, 2N Mobile, AL 36604.
Journal:FP Essent. 2019 Feb;477:11-15.

6:Effectiveness of honey dressing in the treatment of diabetic foot ulcers: A systematic review and meta-analysis.
Authors:Wang C, Guo M, Zhang N, Wang G
Institution:School of Nursing, Shandong University, Jinan, Shandong, China. Electronic address: address: address: address:
Journal:Complement Ther Clin Pract. 2019 Feb;34:123-131. doi: 10.1016/j.ctcp.2018.09.004. Epub 2018 Sep 21.

7:Peripheral Neuropathy.
Authors:Barrell K, Smith AG
Institution:Department of Neurology, University of Utah School of Medicine, 175 North Medical Drive, Salt Lake City, UT 84132, USA. Electronic address: Richmond, VA 23298, USA.
Journal:Med Clin North Am. 2019 Mar;103(2):383-397. doi: 10.1016/j.mcna.2018.10.006. Epub 2018 Dec 17.

8:Pregabalin for neuropathic pain in adults.
Authors:Derry S, Bell RF, Straube S, Wiffen PJ, Aldington D, Moore RA
Institution:Pain Research and Nuffield Department of Clinical Neurosciences (Nuffield Division of Anaesthetics), University of Oxford, Pain Research Unit, Churchill Hospital, Oxford, Oxfordshire, UK, OX3 7LE.
Journal:Cochrane Database Syst Rev. 2019 Jan 23;1:CD007076. doi: 10.1002/14651858.CD007076.pub3.

9:A review of complementary therapies with medicinal plants for chemotherapy-induced peripheral neuropathy.
Authors:Wu BY, Liu CT, Su YL, Chen SY, Chen YH, Tsai MY
Institution:Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; Graduate Institute of Integrated Medicine, College of Chinese Medicine, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, Taiwan. Gung University College of Medicine, Kaohsiung, Taiwan. Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 83301, Taiwan. 82445, Taiwan. Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, Taiwan; Department of Psychology, College of Medical and Health Science, Asia University, Taichung, Taiwan. Electronic address: Gung University College of Medicine, Kaohsiung, Taiwan; Graduate Institute of Integrated Medicine, College of Chinese Medicine, Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, Taiwan. Electronic address:
Journal:Complement Ther Med. 2019 Feb;42:226-232. doi: 10.1016/j.ctim.2018.11.022. Epub 2018 Nov 27.

10:Dose vitamin D supplementations improve peripheral diabetic neuropathy? A before-after clinical trial.
Authors:Ghadiri-Anari A, Mozafari Z, Gholami S, Khodaei SA, Aboutorabi-Zarchi M, Sepehri F, Nadjarzade A, Rahmanian M, Namiranian N
Institution:Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Iran. Iran. Iran. University of Medical Sciences, Yazd, Iran. Iran. Medical Sciences, Yazd, Iran. Iran. Iran. Electronic address:
Journal:Diabetes Metab Syndr. 2019 Jan - Feb;13(1):890-893. doi: 10.1016/j.dsx.2018.12.014. Epub 2018 Dec 20.

11:Topic platelet gel application in chronic diabetic foot ulcers.
Authors:Bini Antunes M, Costa L, Carneiro M, Santos F, Oliveira R, Ferreira A, Sampaio M, Guimaraes R, Pereira J, Neto H, Amil M, Coutinho J, Carvalho R
Institution:Haematology Department, Centro Hospitalar Universitario do Porto, Porto, Portugal. Electronic address:; Diabetic Foot Multidisciplinary Unit, Centro Hospitalar Universitario do Porto, Porto, Portugal.
Journal:Diabetes Metab Syndr. 2019 Jan - Feb;13(1):644-647. doi: 10.1016/j.dsx.2018.11.032. Epub 2018 Nov 17.

12:Efficacy of autologous bone marrow mononuclear cell transplantation therapy in patients with refractory diabetic peripheral neuropathy.
Authors:Mao H, Wei W, Fu XL, Dong JJ, Lyu XY, Jia T, Tang Y, Zhao S
Institution:Department of Endocrinology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, China.; Department of Economics, Nanyang Technological University, Singapore 637332, Singapore.
Journal:Chin Med J (Engl). 2019 Jan 5;132(1):11-16. doi: 10.1097/CM9.0000000000000009.

13:Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.
Authors:Hitchman LH, Totty JP, Raza A, Cai P, Smith GE, Carradice D, Wallace T, Harwood AE, Chetter IC
Institution:Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, UK. Electronic address:
Journal:Ann Vasc Surg. 2019 Apr;56:330-339. doi: 10.1016/j.avsg.2018.10.013. Epub 2018 Nov 26.

14:Early US Experience With Stimulation of the Dorsal Root Ganglia for the Treatment of Peripheral Neuropathy in the Lower Extremities: A Multicenter Retrospective Case Series.
Authors:Falowski S, Pope JE, Raza A
Institution:St. Luke's University Health Network, Bethlehem, PA, USA.
Journal:Neuromodulation. 2019 Jan;22(1):96-100. doi: 10.1111/ner.12860. Epub 2018 Sep 28.

15:Emerging Biomarkers, Tools, and Treatments for Diabetic Polyneuropathy.
Authors:Bonhof GJ, Herder C, Strom A, Papanas N, Roden M, Ziegler D
Institution:Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Dusseldorf, Dusseldorf, Germany.; German Center for Diabetes Research, Munich-Neuherberg, Neuherberg, Partner Dusseldorf, Dusseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany.; Second Department of Internal Medicine, Diabetes Center, Diabetic Foot Clinic, Democritus University of Thrace, Alexandroupolis, Greece.
Journal:Endocr Rev. 2019 Feb 1;40(1):153-192. doi: 10.1210/er.2018-00107.

16:Structural, functional, and symptom relations in painful distal symmetric polyneuropathies: a systematic review.
Authors:Karlsson P, Hincker AM, Jensen TS, Freeman R, Haroutounian S
Institution:Department of Clinical Medicine, Danish Pain Research Center, Aarhus University, Aarhus, Denmark. Aarhus University, Aarhus, Denmark. Louis, MO, United States. Aarhus, Denmark. Medical Center, Boston, MA, United States. Louis, MO, United States. Louis, MO, United States.
Journal:Pain. 2019 Feb;160(2):286-297. doi: 10.1097/j.pain.0000000000001381.

17:Reduced vitamin D levels in painful diabetic peripheral neuropathy.
Authors:Shillo P, Selvarajah D, Greig M, Gandhi R, Rao G, Wilkinson ID, Anand P, Tesfaye S
Institution:Diabetes Research Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield. Sheffield. Sheffield. Sheffield. Sheffield.
Journal:Diabet Med. 2019 Jan;36(1):44-51. doi: 10.1111/dme.13798. Epub 2018 Sep 20.

18:Surgical peripheral nerve decompression for the treatment of painful diabetic neuropathy of the foot - A level 1 pragmatic randomized controlled trial.
Authors:Best TJ, Best CA, Best AA, Fera LA
Institution:Northern Ontario School of Medicine, Sudbury, Canada. Electronic address:
Journal:Diabetes Res Clin Pract. 2019 Jan;147:149-156. doi: 10.1016/j.diabres.2018.08.002. Epub 2018 Aug 4.

19:Prevention and Treatment for Chemotherapy-Induced Peripheral Neuropathy: Therapies Based on CIPN Mechanisms.
Authors:Hu LY, Mi WL, Wu GC, Wang YQ, Mao-Ying QL
Institution:Department of Integrative Medicine and Neurobiology, State Key Laboratory of Medical Neurobiology, Institute of Acupuncture Research, Institutes of Brain Science, Collaborative Innovation Center for Brain Science, School of Basic Medical Science, Fudan University, Shanghai, China.
Journal:Curr Neuropharmacol. 2019;17(2):184-196. doi: 10.2174/1570159X15666170915143217.

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What Our Customers Are Saying...

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